Anti-estrogen steroids which are frequently used today’s drug industry mainly includes: Exemestane, Anastrozole, Letrozole these three, three drugs have their own advantages and disadvantages. Today we are going to compare the three drugs and how do we use them? How many? In fact, anti-estrogen is also important in the steroid cycle.
In the process of steroid cycle, due to the aromatization of some drugs (such as Dianabol and Deca), the body converts some high androgens into estrogen through aromatase, so as to obtain the balance between estrogen and androgens in the body. However, this transformation can lead to fat accumulation, decreased sexual desire, depression, and even breast cancer in men and women. Aromatase inhibitors (AI) are an effective way to solve these problems.
Anastrozole and Letrozole work style completely block aromatase, and the role of Exemestane is aromatic inactivation of enzyme in the body.
But as for anti-estrogen, what should we choose?
In general, Exemestane is 25 mg each tablet dosage for sale, and usually a dose of 12.5 mg of steroid cycle every other day, or 12.5 mg a day, the highest 25 mg per day.
However, estradiol level is not as low as possible in the whole cycle. Generally, when estradiol level is lower than 20pg/mg, symptoms such as depression, decreased libido, muscle leveling or joint pain may be caused by too low estradiol, so the dose of aromatase inhibitor (AI) should be adjusted. For example, users are injected with 250mg of testosterone per week and 750mg of non-aromatized steroids per week. Then the dose of 12.5 mg daily Exemestane can to a certain extent, inhibit estrogen. But if the user put the testosterone dose to 1000 mg every week, we don’t need to put Exemestane dose increase to 50 mg a day, usually in 25 mg is enough to cope with such a high dose of testosterone.
If you use the half-life in steroid cycle supernormal and have strong aromatization drugs such as Deca, then Exemestane in the PCT phase is preferred, rather than Exemestane or Letrozole. Because during PCT we need to naturally return estradiol levels to normal levels rather than completely blocking aromatase and artificially inhibiting it. Because the blocking aromatase accumulates, when the blocking is stopped, the aromatase erupts to some extent.
In the process of PCT, Exemestane dose should be lower than the cycles, because in the blood can aromatization of steroids will reduce a lot. Usually, 12.5mg every other day, or even every three or four days is enough.
Exemestane, Anastrozole, Letrozole that several kinds of aromatase inhibitors can very good control of estrogen transformation, if you are using one of these, then you should continue to use because you can have good control of the dosage. If you haven’t used them before, so can any of the three antiestrogens. It’s just the difference between the effects and the dose.