Exemestane for pct cycle
Exemestane is a steroidal aromatase inhibitors/suicide irreversible aromatase inactivator, by blocking aromatase reduces the production of estrogen in the body. The drug, which is structurally similar to formestan, is used in the treatment of estrogen-dependent breast cancer, are most aromatase inhibitors. It is popular among bodybuilders when it was used to the post pct-cycle.
The function of Exemestane
For strength athletes and bodybuilders, Exemestane several useful features. First of all, Exemestane estrogen can be 85% lower. Doing so will certainly help prevent estrogen-related side effects from aromatase steroids. The drug also boosts users’ testosterone levels, which may be beneficial if used during post-cycle therapy. In addition, there is evidence that Exemestane is likely to raise the level of insulin growth factor of IGF.
Effects of Exemestane
Like other aromatase inhibitors, the effects of Exemestane lipid/cholesterol to the users, there are conflicting information and research. Some studies have shown that Exemestane lipid/cholesterol almost has no impact to the user, and the influence of other research shown that it can be rather serious.
After oral 25 milligrams, Exemestane2 hours peak plasma concentration. The effective life of this medicine is between 24 and 30 hours. This is important because it is much shorter than nsaids. Single oral 25 milligrams Exemestane will result in plasma and urine estrogen levels decline in a relatively long time, about 2 to 3 days after taking a maximum inhibition, and last about 4 to 5 days.
Research shows that 25 milligrams of Exemestane improves the level of testosterone and estrogen as welll as levels of IGF is basically as effective as 50 mg. Therefore, a daily dose of more than 25 milligrams is not necessary. Due to the activity of Exemestane, it is suggested taking it about every 24 hours.
The only negative effect of the compound from the dose plan is that it takes about seven days to reach stable plasma levels. However, this is not the main barrier to its use. It simply needs a week before the users fully realize the effect of compound Exemestane came into use.
Side effects when using Exemestane
Exemestane under the dose of 600 mg/day is no significant drug toxicity. Most users are well tolerated and the maximum tolerable dose of toxicity has not been determined. Adverse side effects associated with the use of this compound are usually very mild and may include transient gastrointestinal reactions, hot flashes, nausea and/or fatigue. As noted earlier, the effect of esimetan on lipids/cholesterol is unknown and should therefore be monitored when the compound is used.
Exemestane is a relatively safe in aromatic steroid inhibitors, due to the compound has a moderate negative side effects, should be used under the guidance.