Enobosarm, commonly known as Ostarine or MK 2866, is a selective androgen receptor regulator (SARM) developed by GTx (GTx-024) to combat muscular atrophy and osteoporosis. Many speculate that Ostarine could be used in hormone replacement therapy programs, as well as to treat sarcopenia, cachexia and muscular dystrophy. This is a valuable benefit for people with muscular dystrophy because SARM has been shown to have no effect on non-skeletal muscles.
As SARM, Ostarine binds directly to androgen receptors. Although anabolic steroids also bind to androgen receptors, SARM does not convert to DHT or estrogen. MK 2866 aims at a direct anabolic activity. MK 2866 can be used for muscle growth or muscle preservation (depending on diet).
Like anabolic steroids, Ostarine increases protein synthesis and nitrogen retention. However, unlike anabolic steroids, it does not require any DHT or estrogen conversion. Although there was no direct conversion of estrogen in aromatase activity, there was a slight increase in estrogen levels. This may be why Ostarine has been shown to be beneficial to joint health and healing. Estrogen is often considered bad packaging, but some are necessary for health and physical performance. However, the most important is direct binding to the receptor, because it not only promotes anabolism but also directly changes the gene sequence of the receptor location; In fact, it is highly tissue-specific, musculoskeletal.
The half-life of MK 2866 is about 24 hours.
Effects of Ostarine MK 2866
Ostarine can be used to increase and maintain muscle mass. For athletes, this means it can be used in cutting and swelling stages. Users can expect a significant increase in lean weight without unnecessary water retention or concerns about gynecomastia, which is often associated with anabolic steroids. A person is unlikely to gain as much weight as he does from a cycle of Dianabol or Anadrol; However, the benefits are cleaner and easier to maintain. When using certain steroids, people usually associate all weight gain with positive weight gain, but only lean muscle gain counts.
Ostarine is also very useful during the weight loss or diet phase. This may be the best time to use the Sarms to protect muscles. In order to lose weight, you have to burn more calories than you burn. Being under caloric puts lean muscle at risk and some of the loss can occur. If we can protect our muscles in our diet, not only will we look better, we’ll actually continue to burn fat. Muscle loss can hamper metabolism, making it difficult to lose fat. By protecting your muscles, you protect your metabolism. MK 2866 will also provide important joint healing and repair, which is invaluable when dieting. Strict dieting often leads to joint discomfort. If we can protect our joints while increasing the strength of tendons and ligaments, collagen synthesis and bone mineral content, we can continue to train and work harder. MK 2866’s effects in this manner are indeed beneficial during the expansion or cutting phase, but they are usually more prominent during the cutting phase. Ostarine’s role in this area is so powerful that the data suggest that it can directly treat injuries, rather than covering them up like painkillers, but actually heal joints, ligaments, tendons, and bones.